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Role of μ-Calpain in Proteolytic Cleavage of Brain L-glutamic Acid Decarboxylase

Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for γ-aminobutyric acid (GABA) biosynthesis. Previously, we reported the presence of truncated forms of GAD in vivo and in vitro. In addition, an unidentified endogenous protease responsible for proteolytic cleavage of full-length GAD (fG...

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Detalhes bibliográficos
Main Authors: Sha, Di, Jin, Ying, Wu, Heng, Wei, Jianning, Lin, Chun-Hua, Lee, Yi-Hsuan, Buddhala, Chandana, Kuchay, Shafi, Chishti, Athar H., Wu, Jang-Yen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447620/
https://ncbi.nlm.nih.gov/pubmed/18377878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.02.033
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