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Role of μ-Calpain in Proteolytic Cleavage of Brain L-glutamic Acid Decarboxylase

Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for γ-aminobutyric acid (GABA) biosynthesis. Previously, we reported the presence of truncated forms of GAD in vivo and in vitro. In addition, an unidentified endogenous protease responsible for proteolytic cleavage of full-length GAD (fG...

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Autors principals: Sha, Di, Jin, Ying, Wu, Heng, Wei, Jianning, Lin, Chun-Hua, Lee, Yi-Hsuan, Buddhala, Chandana, Kuchay, Shafi, Chishti, Athar H., Wu, Jang-Yen
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447620/
https://ncbi.nlm.nih.gov/pubmed/18377878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.02.033
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