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Ras Binding Triggers Ubiquitination of the Ras Exchange Factor Ras-GRF2

Ras is a small GTPase that is activated by upstream guanine nucleotide exchange factors, one of which is Ras-GRF2. GRF2 is a widely expressed protein with several recognizable sequence motifs, including a Ras exchanger motif (REM), a PEST region containing a destruction box (DB), and a Cdc25 domain....

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Udgivet i:Mol Cell Biol
Principais autores: de Hoog, Carmen L., Koehler, Jackie A., Goldstein, Marni D., Taylor, Paul, Figeys, Daniel, Moran, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86827/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.6.2107-2117.2001
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