Functional Regions of Human Telomerase Reverse Transcriptase and Human Telomerase RNA Required for Telomerase Activity and RNA-Protein Interactions

Telomerase is a specialized reverse transcriptase (RT) that is minimally composed of a protein catalytic subunit and an RNA component. The RNA subunit contains a short template sequence that directs the synthesis of DNA repeats at the ends of chromosomes. Human telomerase activity can be reconstitut...

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Bibliographic Details
Main Authors: Bachand, François, Autexier, Chantal
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86762/
https://ncbi.nlm.nih.gov/pubmed/11238925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1888-1897.2001
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