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Functional Regions of Human Telomerase Reverse Transcriptase and Human Telomerase RNA Required for Telomerase Activity and RNA-Protein Interactions

Telomerase is a specialized reverse transcriptase (RT) that is minimally composed of a protein catalytic subunit and an RNA component. The RNA subunit contains a short template sequence that directs the synthesis of DNA repeats at the ends of chromosomes. Human telomerase activity can be reconstitut...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Bachand, François, Autexier, Chantal
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1888-1897.2001
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