A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

The p53 protein is related by sequence homology and function to the products of two other genes, p63 and p73, that each encode several isoforms. We and others have discovered previously that certain tumor-derived mutants of p53 can associate and inhibit transcriptional activation by the α and β isof...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Gaiddon, C., Lokshin, M., Ahn, J., Zhang, T., Prives, C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1874-1887.2001
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