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c-myc Internal Ribosome Entry Site Activity Is Developmentally Controlled and Subjected to a Strong Translational Repression in Adult Transgenic Mice

The expression of c-myc proto-oncogene, a key regulator of cell proliferation and apoptosis, is controlled at different transcriptional and posttranscriptional levels. In particular, the c-myc mRNA contains an internal ribosome entry site (IRES) able to promote translation initiation independently f...

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Udgivet i:Mol Cell Biol
Principais autores: Créancier, Laurent, Mercier, Pascale, Prats, Anne-Catherine, Morello, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1833-1840.2001
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