c-myc Internal Ribosome Entry Site Activity Is Developmentally Controlled and Subjected to a Strong Translational Repression in Adult Transgenic Mice

The expression of c-myc proto-oncogene, a key regulator of cell proliferation and apoptosis, is controlled at different transcriptional and posttranscriptional levels. In particular, the c-myc mRNA contains an internal ribosome entry site (IRES) able to promote translation initiation independently f...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Créancier, Laurent, Mercier, Pascale, Prats, Anne-Catherine, Morello, Dominique
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1833-1840.2001
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