c-myc Internal Ribosome Entry Site Activity Is Developmentally Controlled and Subjected to a Strong Translational Repression in Adult Transgenic Mice

The expression of c-myc proto-oncogene, a key regulator of cell proliferation and apoptosis, is controlled at different transcriptional and posttranscriptional levels. In particular, the c-myc mRNA contains an internal ribosome entry site (IRES) able to promote translation initiation independently f...

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Detalhes bibliográficos
Main Authors: Créancier, Laurent, Mercier, Pascale, Prats, Anne-Catherine, Morello, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86749/
https://ncbi.nlm.nih.gov/pubmed/11238920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1833-1840.2001
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