Early Embryonic Lethality in PARP-1 Atm Double-Mutant Mice Suggests a Functional Synergy in Cell Proliferation during Development

PARP-1 and ATM are both involved in the response to DNA strand breaks, resulting in induction of a signaling network responsible for DNA surveillance, cellular recovery, and cell survival. ATM interacts with double-strand break repair pathways and induces signals resulting in the control of the cell...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Murcia, Josiane Ménissier-de, Mark, Manuel, Wendling, Olivia, Wynshaw-Boris, Anthony, de Murcia, Gilbert
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2001
Aiheet:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1828-1832.2001
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