Functional Analysis of the Leukemia Protein ELL: Evidence for a Role in the Regulation of Cell Growth and Survival

The ELL gene encodes an RNA polymerase II transcription factor that frequently undergoes translocation with the MLL gene in acute human myeloid leukemia. Here, we report that ELL can regulate cell proliferation and survival. In order to better understand the physiological role of the ELL protein, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnstone, Ricky W., Gerber, Mark, Landewe, Theresa, Tollefson, Anne, Wold, William S., Shilatifard, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2001
Pynciau:
Transcriptional Regulation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC86713/
https://ncbi.nlm.nih.gov/pubmed/11238904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1672-1681.2001
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg