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Molecular Basis of p53 Functional Inactivation by the Leukemic Protein MLL-ELL

The Eleven Lysine-rich Leukemia (ELL) gene undergoes translocation and fuses in frame to the Multiple Lineage Leukemia (MLL) gene in a substantial proportion of patients suffering from acute forms of leukemia. Molecular mechanisms of cellular transformation by the MLL-ELL fusion are not well underst...

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Hlavní autoři: Wiederschain, Dmitri, Kawai, Hidehiko, Gu, JiJie, Shilatifard, Ali, Yuan, Zhi-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156137/
https://ncbi.nlm.nih.gov/pubmed/12773566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4230-4246.2003
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