Functional Analysis of the Leukemia Protein ELL: Evidence for a Role in the Regulation of Cell Growth and Survival

The ELL gene encodes an RNA polymerase II transcription factor that frequently undergoes translocation with the MLL gene in acute human myeloid leukemia. Here, we report that ELL can regulate cell proliferation and survival. In order to better understand the physiological role of the ELL protein, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnstone, Ricky W., Gerber, Mark, Landewe, Theresa, Tollefson, Anne, Wold, William S., Shilatifard, Ali
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86713/
https://ncbi.nlm.nih.gov/pubmed/11238904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1672-1681.2001
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