Insight into Mammalian Selenocysteine Insertion: Domain Structure and Ribosome Binding Properties of Sec Insertion Sequence Binding Protein 2

The cotranslational incorporation of the unusual amino acid selenocysteine (Sec) into both prokaryotic and eukaryotic proteins requires the recoding of a UGA stop codon as one specific for Sec. The recognition of UGA as Sec in mammalian selenoproteins requires a Sec insertion sequence (SECIS) elemen...

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Detalhes bibliográficos
Main Authors: Copeland, Paul R., Stepanik, Vincent A., Driscoll, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86695/
https://ncbi.nlm.nih.gov/pubmed/11238886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1491-1498.2001
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