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The L7Ae RNA Binding Motif Is a Multifunctional Domain Required for the Ribosome-Dependent Sec Incorporation Activity of Sec Insertion Sequence Binding Protein 2

The decoding of specific UGA codons as selenocysteine is specified by the Sec insertion sequence (SECIS) element. Additionally, Sec-tRNA([Ser]Sec) and the dedicated Sec-specific elongation factor eEFSec are required but not sufficient for nonsense suppression. SECIS binding protein 2 (SBP2) is also...

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Detalhes bibliográficos
Main Authors: Caban, Kelvin, Kinzy, Scott A., Copeland, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099609/
https://ncbi.nlm.nih.gov/pubmed/17636016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00632-07
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