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VHL Induces Renal Cell Differentiation and Growth Arrest through Integration of Cell-Cell and Cell-Extracellular Matrix Signaling
Mutations in the von Hippel-Lindau (VHL) gene are involved in the family cancer syndrome for which it is named and the development of sporadic renal cell cancer (RCC). Reintroduction of VHL into RCC cells lacking functional VHL [VHL(−)] can suppress their growth in nude mice, but not under standard...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86677/ https://ncbi.nlm.nih.gov/pubmed/11154273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.865-874.2001 |
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