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Basal Extracellular Signal-Regulated Kinase Activity Modulates Cell-Cell and Cell-Matrix Interactions

Suppression of the basal extracellular signal-regulated kinase (ERK) activity in PC12 cells markedly altered their phenotype. Wild-type cells grew in a dissociated pattern adherent to the substrate. The stable expression of an ERK inhibitory mutant resulted in the formation of calcium-dependent aggr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Qun, Paredes, Mercedes, Zhang, Jimin, Kosik, Kenneth S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108907/
https://ncbi.nlm.nih.gov/pubmed/9584166
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