A carregar...
HIF-2α downregulation in the absence of functional VHL is not sufficient for renal cell differentiation
BACKGROUND: Mutational inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene has been linked to hereditary as well as sporadic clear cell renal carcinomas. The product of the VHL gene, pVHL, acts to target hypoxia-inducible factor alpha (HIF-α) subunits for ubiquitination and subsequent...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919349/ https://ncbi.nlm.nih.gov/pubmed/17598890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-13 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|