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Oligomerization of DH Domain Is Essential for Dbl-Induced Transformation
The dbl oncogene product (onco-Dbl) is the prototype member of a family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. The Dbl homology (DH) domain of onco-Dbl is responsible for the GEF catalytic activity, and the DH domain, together with the immediately adjacent pleckstrin homology...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86589/ https://ncbi.nlm.nih.gov/pubmed/11134331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.425-437.2001 |
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