Oligomerization of DH Domain Is Essential for Dbl-Induced Transformation
The dbl oncogene product (onco-Dbl) is the prototype member of a family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. The Dbl homology (DH) domain of onco-Dbl is responsible for the GEF catalytic activity, and the DH domain, together with the immediately adjacent pleckstrin homology...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.425-437.2001 |
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