Oligomerization of DH Domain Is Essential for Dbl-Induced Transformation

The dbl oncogene product (onco-Dbl) is the prototype member of a family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. The Dbl homology (DH) domain of onco-Dbl is responsible for the GEF catalytic activity, and the DH domain, together with the immediately adjacent pleckstrin homology...

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Detalhes bibliográficos
Main Authors: Zhu, Kejin, Debreceni, Balazs, Bi, Feng, Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86589/
https://ncbi.nlm.nih.gov/pubmed/11134331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.425-437.2001
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