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Sonic hedgehog Promotes G(1) Cyclin Expression and Sustained Cell Cycle Progression in Mammalian Neuronal Precursors

Sonic hedgehog (Shh) signal transduction via the G-protein-coupled receptor, Smoothened, is required for proliferation of cerebellar granule neuron precursors (CGNPs) during development. Activating mutations in the Hedgehog pathway are also implicated in basal cell carcinoma and medulloblastoma, a t...

詳細記述

保存先:
書誌詳細
主要な著者: Kenney, Anna Marie, Rowitch, David H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC86558/
https://ncbi.nlm.nih.gov/pubmed/11074003
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