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mRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E

A major pathway of eukaryotic mRNA turnover occurs by deadenylation-dependent decapping that exposes the transcript to 5′→3′ exonucleolytic degradation. A critical step in this pathway is decapping, since removal of the cap structure permits 5′→3′ exonucleolytic digestion. Based on alterations in mR...

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Bibliografische gegevens
Hoofdauteurs: Schwartz, David C., Parker, Roy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86404/
https://ncbi.nlm.nih.gov/pubmed/11027264
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