mRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E

A major pathway of eukaryotic mRNA turnover occurs by deadenylation-dependent decapping that exposes the transcript to 5′→3′ exonucleolytic degradation. A critical step in this pathway is decapping, since removal of the cap structure permits 5′→3′ exonucleolytic digestion. Based on alterations in mR...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Schwartz, David C., Parker, Roy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027264/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.21.7933-7942.2000
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