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Inhibition of ErbB-2 Mitogenic and Transforming Activity by RALT, a Mitogen-Induced Signal Transducer Which Binds to the ErbB-2 Kinase Domain

The product of rat gene 33 was identified as an ErbB-2-interacting protein in a two-hybrid screen employing the ErbB-2 juxtamembrane and kinase domains as bait. This interaction was reproduced in vitro with a glutathione S-transferase fusion protein spanning positions 282 to 395 of the 459-residue g...

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Publicado en:Mol Cell Biol
Autores principales: Fiorentino, Loredana, Pertica, Chiara, Fiorini, Monia, Talora, Claudio, Crescenzi, Marco, Castellani, Loriana, Alemà, Stefano, Benedetti, Piero, Segatto, Oreste
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7735-7750.2000
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