Inhibition of ErbB-2 Mitogenic and Transforming Activity by RALT, a Mitogen-Induced Signal Transducer Which Binds to the ErbB-2 Kinase Domain

The product of rat gene 33 was identified as an ErbB-2-interacting protein in a two-hybrid screen employing the ErbB-2 juxtamembrane and kinase domains as bait. This interaction was reproduced in vitro with a glutathione S-transferase fusion protein spanning positions 282 to 395 of the 459-residue g...

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Autors principals: Fiorentino, Loredana, Pertica, Chiara, Fiorini, Monia, Talora, Claudio, Crescenzi, Marco, Castellani, Loriana, Alemà, Stefano, Benedetti, Piero, Segatto, Oreste
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86354/
https://ncbi.nlm.nih.gov/pubmed/11003669
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