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Nonperiodic Activity of the Human Anaphase-Promoting Complex–Cdh1 Ubiquitin Ligase Results in Continuous DNA Synthesis Uncoupled from Mitosis

Ubiquitin-proteasome-mediated destruction of rate-limiting proteins is required for timely progression through the main cell cycle transitions. The anaphase-promoting complex (APC), periodically activated by the Cdh1 subunit, represents one of the major cellular ubiquitin ligases which, in Saccharom...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Sørensen, Claus Storgaard, Lukas, Claudia, Kramer, Edgar R., Peters, Jan-Michael, Bartek, Jiri, Lukas, Jiri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86321/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7613-7623.2000
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