Increased Rates of Genomic Deletions Generated by Mutations in the Yeast Gene Encoding DNA Polymerase δ or by Decreases in the Cellular Levels of DNA Polymerase δ

In Saccharomyces cerevisiae, POL3 encodes the catalytic subunit of DNA polymerase δ. While yeast POL3 mutant strains that lack the proofreading exonuclease activity of the polymerase have a strong mutator phenotype, little is known regarding the role of other Pol3p domains in mutation avoidance. We...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Kokoska, Robert J., Stefanovic, Lela, DeMai, Jeremy, Petes, Thomas D.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2000
Предметы:	DNA Dynamics and Chromosome Structure
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7490-7504.2000
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