Increased Rates of Genomic Deletions Generated by Mutations in the Yeast Gene Encoding DNA Polymerase δ or by Decreases in the Cellular Levels of DNA Polymerase δ

In Saccharomyces cerevisiae, POL3 encodes the catalytic subunit of DNA polymerase δ. While yeast POL3 mutant strains that lack the proofreading exonuclease activity of the polymerase have a strong mutator phenotype, little is known regarding the role of other Pol3p domains in mutation avoidance. We...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Kokoska, Robert J., Stefanovic, Lela, DeMai, Jeremy, Petes, Thomas D.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7490-7504.2000
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