In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions

The promyelocytic leukemia zinc finger (PLZF) protein is a transcription factor disrupted in patients with t(11;17)(q23;q21)-associated acute promyelocytic leukemia. PLZF contains an N-terminal BTB/POZ domain which is required for dimerization, transcriptional repression, formation of high-molecular...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Melnick, Ari, Ahmad, K. Farid, Arai, Sally, Polinger, Adam, Ball, Helen, Borden, Katherine L., Carlile, Graeme W., Prive, Gilbert G., Licht, Jonathan D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6550-6567.2000
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