Insulin-Activated Protein Kinase Cβ Bypasses Ras and Stimulates Mitogen-Activated Protein Kinase Activity and Cell Proliferation in Muscle Cells

In L6 muscle cells expressing wild-type human insulin receptors (L6hIR), insulin induced protein kinase Cα (PKCα) and β activities. The expression of kinase-deficient IR mutants abolished insulin stimulation of these PKC isoforms, indicating that receptor kinase is necessary for PKC activation by in...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Formisano, Pietro, Oriente, Francesco, Fiory, Francesca, Caruso, Matilde, Miele, Claudia, Maitan, Maria Alessandra, Andreozzi, Francesco, Vigliotta, Giovanni, Condorelli, Gerolama, Beguinot, Francesco
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2000
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6323-6333.2000
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