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Termination and Peptide Release at the Upstream Open Reading Frame Are Required for Downstream Translation on Synthetic Shunt-Competent mRNA Leaders

We have shown recently that a stable hairpin preceded by a short upstream open reading frame (uORF) promotes nonlinear ribosome migration or ribosome shunt on a synthetic mRNA leader (M. Hemmings-Mieszczak and T. Hohn, RNA 5:1149–1157, 1999). We have now used the model mRNA leader to study further t...

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Udgivet i:Mol Cell Biol
Principais autores: Hemmings-Mieszczak, Maja, Hohn, Thomas, Preiss, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6212-6223.2000
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