Termination and Peptide Release at the Upstream Open Reading Frame Are Required for Downstream Translation on Synthetic Shunt-Competent mRNA Leaders

We have shown recently that a stable hairpin preceded by a short upstream open reading frame (uORF) promotes nonlinear ribosome migration or ribosome shunt on a synthetic mRNA leader (M. Hemmings-Mieszczak and T. Hohn, RNA 5:1149–1157, 1999). We have now used the model mRNA leader to study further t...

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Main Authors: Hemmings-Mieszczak, Maja, Hohn, Thomas, Preiss, Thomas
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
主題:
Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC86096/
https://ncbi.nlm.nih.gov/pubmed/10938098
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