Upstream open reading frames located in the leader of protein kinase Mζ mRNA regulate its translation

For protein synthesis that occurs locally in dendrites, the translational control mechanisms are much more important for neuronal functioning than the transcription levels. Here, we show that uORFs (upstream open reading frames) in the 5’ untranslated region (5’UTR) play a critical role in regulatio...

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主要な著者:	Natalia V Bal, Denis Susorov, Ekaterina Chesnokova, Artem Kasianov, Tatiana Mikhailova, Elena Alkalaeva, Pavel M. Balaban, Peter Kolosov
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2016-10-01
シリーズ:	Frontiers in Molecular Neuroscience
主題:	translational control local protein synthesis UORF PKMζ eIF2a phosphorylation
オンライン･アクセス:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00103/full
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