BCR-ABL Prevents c-Jun-Mediated and Proteasome-Dependent FUS (TLS) Proteolysis through a Protein Kinase CβII-Dependent Pathway

The DNA binding activity of FUS (also known as TLS), a nuclear pro-oncogene involved in multiple translocations, is regulated by BCR-ABL in a protein kinase CβII (PKCβII)-dependent manner. We show here that in normal myeloid progenitor cells FUS, although not visibly ubiquitinated, undergoes proteas...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Perrotti, Danilo, Iervolino, Angela, Cesi, Vincenzo, Cirinná, Maria, Lombardini, Silvia, Grassilli, Emanuela, Bonatti, Silvia, Claudio, Pier Paolo, Calabretta, Bruno
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2000
Subjects:	Cell Growth and Development
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.6159-6169.2000
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