A Genetic Screen for Human Genes Suppressing FUS Induced Toxicity in Yeast
FUS is a nucleic acid binding protein that, when mutated, cause a subset of familial amyotrophic lateral sclerosis (ALS). Expression of FUS in yeast recapitulates several pathological features of the disease-causing mutant proteins, including nuclear to cytoplasmic translocation, formation of cytopl...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020-06-01
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| Serie: | G3: Genes, Genomes, Genetics |
| Soggetti: | |
| Accesso online: | http://g3journal.org/lookup/doi/10.1534/g3.120.401164 |
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