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Physical Association of Eukaryotic Initiation Factor 4G (eIF4G) with eIF4A Strongly Enhances Binding of eIF4G to the Internal Ribosomal Entry Site of Encephalomyocarditis Virus and Is Required for Internal Initiation of Translation

Mammalian eukaryotic initiation factor 4GI (eIF4GI) may be divided into three similarly sized regions. The central region (amino acids [aa] 613 to 1090) binds eIF3, eIF4A, and the encephalomyocarditis virus (EMCV) internal ribosomal entry site (IRES) and mediates initiation on this RNA. We identifie...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Lomakin, Ivan B., Hellen, Christopher U. T., Pestova, Tatyana V.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913184/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.6019-6029.2000
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