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Receptor Isoforms Mediate Opposing Proliferative Effects through Gβγ-Activated p38 or Akt Pathways

The opposing effects on proliferation mediated by G-protein-coupled receptor isoforms differing in their COOH termini could be correlated with the abilities of the receptors to differentially activate p38, implicated in apoptotic events, or phosphatidylinositol 3-kinase (PI 3-K), which provides a so...

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Publicado no:Mol Cell Biol
Principais autores: Sellers, Lynda A., Alderton, Forbes, Carruthers, Alan M., Schindler, Marcus, Humphrey, Patrick P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5974-5985.2000
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