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Adeno-associated virus vector mediated expression of an oncogenic retroviral envelope protein induces lung adenocarcinomas in immunocompetent mice.

Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate of 16% necessitates the need for novel treatment strategies. Mouse models of lung cancer are important tools for analyzing the significance of somatic mutations in the initiation and progression of l...

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Huvudupphov: Nicolle M Linnerth-Petrik, Lisa A Santry, Darrick L Yu, Sarah K Wootton
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3519541?pdf=render
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