Mitochondrial Protein Import Motor: the ATPase Domain of Matrix Hsp70 Is Crucial for Binding to Tim44, while the Peptide Binding Domain and the Carboxy-Terminal Segment Play a Stimulatory Role

The import motor for preproteins that are targeted into the mitochondrial matrix consists of the matrix heat shock protein Hsp70 (mtHsp70) and the translocase subunit Tim44 of the inner membrane. mtHsp70 interacts with Tim44 in an ATP-dependent reaction cycle, binds to preproteins in transit, and dr...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Krimmer, Thomas, Rassow, Joachim, Kunau, Wolf-H., Voos, Wolfgang, Pfanner, Nikolaus
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2000
Témata:	Cell and Organelle Structure and Assembly
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5879-5887.2000
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