Mitochondrial Protein Import Motor: the ATPase Domain of Matrix Hsp70 Is Crucial for Binding to Tim44, while the Peptide Binding Domain and the Carboxy-Terminal Segment Play a Stimulatory Role

The import motor for preproteins that are targeted into the mitochondrial matrix consists of the matrix heat shock protein Hsp70 (mtHsp70) and the translocase subunit Tim44 of the inner membrane. mtHsp70 interacts with Tim44 in an ATP-dependent reaction cycle, binds to preproteins in transit, and dr...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Krimmer, Thomas, Rassow, Joachim, Kunau, Wolf-H., Voos, Wolfgang, Pfanner, Nikolaus
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Cell and Organelle Structure and Assembly
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5879-5887.2000
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!