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Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

Aldose reductase (ALR2) is thought to be involved in the pathogenesis of various diseases associated with diabetes mellitus, such as cataract, retinopathy, neuropathy, and nephropathy. However, its physiological functions are not well understood. We developed mice deficient in this enzyme and found...

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Publicado no:Mol Cell Biol
Principais autores: Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2000
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5840-5846.2000
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