Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

Aldose reductase (ALR2) is thought to be involved in the pathogenesis of various diseases associated with diabetes mellitus, such as cataract, retinopathy, neuropathy, and nephropathy. However, its physiological functions are not well understood. We developed mice deficient in this enzyme and found...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2000
Предметы:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5840-5846.2000
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Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

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