Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

Aldose reductase (ALR2) is thought to be involved in the pathogenesis of various diseases associated with diabetes mellitus, such as cataract, retinopathy, neuropathy, and nephropathy. However, its physiological functions are not well understood. We developed mice deficient in this enzyme and found...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 2000
נושאים:	Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5840-5846.2000
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