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Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

Aldose reductase (ALR2) is thought to be involved in the pathogenesis of various diseases associated with diabetes mellitus, such as cataract, retinopathy, neuropathy, and nephropathy. However, its physiological functions are not well understood. We developed mice deficient in this enzyme and found...

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Detalhes bibliográficos
Main Authors: Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86061/
https://ncbi.nlm.nih.gov/pubmed/10913167
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