Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus

Aldose reductase (ALR2) is thought to be involved in the pathogenesis of various diseases associated with diabetes mellitus, such as cataract, retinopathy, neuropathy, and nephropathy. However, its physiological functions are not well understood. We developed mice deficient in this enzyme and found...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.5840-5846.2000
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