Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B (PKB) activation and translocation to the cell surface. Wild-type and PDK1 mutants were transfected into HeLa cells, and their subcellular localization was analyzed. PDK1 was found t...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Filippa, Nathalie, Sable, Carol L., Hemmings, Brian A., Van Obberghen, Emmanuel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5712-5721.2000
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!