Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B (PKB) activation and translocation to the cell surface. Wild-type and PDK1 mutants were transfected into HeLa cells, and their subcellular localization was analyzed. PDK1 was found t...

Celý popis

Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Filippa, Nathalie, Sable, Carol L., Hemmings, Brian A., Van Obberghen, Emmanuel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2000
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5712-5721.2000
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!