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Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B (PKB) activation and translocation to the cell surface. Wild-type and PDK1 mutants were transfected into HeLa cells, and their subcellular localization was analyzed. PDK1 was found t...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Filippa, Nathalie, Sable, Carol L., Hemmings, Brian A., Van Obberghen, Emmanuel
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891507/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5712-5721.2000
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