Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

In this report we investigated the function of phosphoinositide-dependent protein kinase 1 (PDK1) in protein kinase B (PKB) activation and translocation to the cell surface. Wild-type and PDK1 mutants were transfected into HeLa cells, and their subcellular localization was analyzed. PDK1 was found t...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Filippa, Nathalie, Sable, Carol L., Hemmings, Brian A., Van Obberghen, Emmanuel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5712-5721.2000
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