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Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

To determine the physiological roles of peroxisome proliferator-activated receptor β (PPARβ), null mice were constructed by targeted disruption of the ligand binding domain of the murine PPARβ gene. Homozygous PPARβ-null term fetuses were smaller than controls, and this phenotype persisted postnatal...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Peters, Jeffrey M., Lee, Susanna S. T., Li, Wen, Ward, Jerrold M., Gavrilova, Oksana, Everett, Carrie, Reitman, Marc L., Hudson, Lynn D., Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85961/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.5119-5128.2000
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