Peroxisome Proliferator-Activated Receptor γ Controls Muc1 Transcription in Trophoblasts

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is essential for placental development. Here, we show that the mucin gene Muc1 is a PPARγ target, whose expression is lost in PPARγ null placentas. During differentiation of trophoblast stem cells, PPARγ is strongly induced, a...

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Hlavní autoři: Shalom-Barak, Tali, Nicholas, Jill M., Wang, Yongxu, Zhang, Xiaowen, Ong, Estelita S., Young, Timothy H., Gendler, Sandra J., Evans, Ronald M., Barak, Yaacov
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC533980/
https://ncbi.nlm.nih.gov/pubmed/15572671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10661-10669.2004
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