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Postcleavage Sequence Specificity in V(D)J Recombination

Unintended DNA rearrangements in a differentiating lymphocyte can have severe, oncogenic consequences, but the mechanisms for avoiding pathogenic outcomes in V(D)J recombination are not well understood. The first level at which fidelity is instituted is in discrimination by the recombination protein...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Agard, Emily A., Lewis, Susanna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.5032-5040.2000
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