The Fanconi Anemia Protein FANCC Binds to and Facilitates the Activation of STAT1 by Gamma Interferon and Hematopoietic Growth Factors

Hematopoietic progenitor cells from Fanconi anemia (FA) group C (FA-C) patients display hypersensitivity to the apoptotic effects of gamma interferon (IFN-γ) and constitutively express a variety of IFN-dependent genes. Paradoxically, however, STAT1 activation is suppressed in IFN-stimulated FA cells...

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Autores principales: Pang, Qishen, Fagerlie, Sara, Christianson, Tracy A., Keeble, Winifred, Faulkner, Greg, Diaz, Jane, Rathbun, R. Keaney, Bagby, Grover C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC85895/
https://ncbi.nlm.nih.gov/pubmed/10848598
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